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有關 Ubiquitin ligase?tw 的學術文章scholar.google.com › citations。

A substrate-trapping strategy to find E3 ubiquitin ligase ... - Nature。

2020年10月20日 · The eluted peptides were desalted using GL-Tip SDB and GL-Tip GC before LC–MS analysis. Mass spectrometry analysis of diGly peptides. Desalted ...。

A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations ... - Frontiers。

2018年2月14日 · There are an estimated 600–700 E3 ligase genes representing ~5% of the human genome. Not surprisingly, mutations in E3 ligase genes have ...。

Ubiquitin-Dependent Sorting in Endocytosis - NCBI。

Substrates can be bound directly by the E3 ligase or by adaptor proteins that in turn bind to ligases, and selection of substrate residues that undergo ...： tw | tw。

Structural insights into the catalysis and regulation of E3 ubiquitin ...。

2018年11月1日 · Ubiquitin ligases (E3s) catalyze the final step of ubiquitin conjugation by transferring ... Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, ...。

Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self ...。

2E), but RNF144A-GL/3L259R failed to promote ubiquitination of DNA-PKcs. Taken together, we conclude that the E3 ligase activity of RNF144A requires GXXXG motif ...。

E3 Ubiquitin Ligases: Ubiquitous Actors in Plant Development and ...。

2017年5月25日 · Protein ubiquitination, including the sequential performances of ubiquitin-activating (E1), ubiquitin-conjugating (E2) and ubiquitin ligase ...。

Screening for E3-Ubiquitin ligase inhibitors: challenges and。

2014年9月30日 · This ubiquitin charged E2 now binds an E3 ligase which catalyses ... Knight RA, Mak TW and Melino G. Neuronal differentiation by TAp73 is ...。

The Class I E3 Ubiquitin Ligase TRIM67 Modulates Brain ... - bioRxiv。

2017年12月30日 · E3 ubiquitin ligases mediate covalent attachment of ubiquitin to ... 2A, Trim67fl) by flanking exon one and ~200 bp upstream of the ATG ...。

Targeted modulation of E3 ligases using engineered ubiquitin variants。

2020年8月31日 · Email; Facebook; Twitter; Linked In; Reddit; Wechat ... Not surprisingly, the malfunction of E3 ligases is directly implicated in many human ...。

Bacterial E3 Ligases That Exploit the Eukaryotic Ubiquitin Machinery。

2014年8月14日 · In eukaryotic cells there are two general classes of E3 ubiquitin ligases. The HECT (Homologous to E6-AP Carboxyl Terminus) and Ring Between ...：